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Related Articles, Links Association between glutathione S-transferase M1 gene deletion and genetic susceptibility to endometriosis. Individuals with GSTM1 null genotype were exposed to risks for endometriosis 2. Related Articles, Links Isolated umbilical endometriosis—a rare finding.

There was no evidence of endometrotic deposits elsewhere. Apart from cyclical bleeding from the umbilicus, she was relatively free of any of the other s and symptoms of Endometriosis. She had excision of the endometeriotic lesion and responded favourably to treatment. A high index of suspicion is required in making a diagnosis of endometriosis in remote extra pelvic sites especially with little or no characterisitic pointers to the disease.

Related Articles, Links Sonovaginography is a new technique for assessing rectovaginal endometriosis. The latter is based on transvaginal ultrasonography combined with the introduction of saline solution to the vagina that creates an acoustic window between the transvaginal probe and the surrounding structures of the vagina.

Ultrasound findings were compared with the of surgical exploration and histological examination. RESULT S : Sonovaginography diagnosed rectovaginal endometriosis more accurately than did transvaginal ultrasonography, with a sensitivity and specificity of Patient discomfort did not differ ificantly between the procedures.

Related Articles, Links Role of reactive oxygen species in the pathophysiology of human reproduction. In male-factor infertility. Reactive oxygen species induced DNA damage may accelerate the process of germ cell apoptosis, leading to the decline in sperm counts associated with male infertility. ROS mediated female fertility disorders share many pathogenic similarities with the ones on the male side. These similarities include a potential role in the pathophysiology of endometriosis and unexplained infertility.

Moreover, oxidative stress may be responsible in hydrosalpingeal fluid mediated embryotoxicity as well as poor in vitro embryonic development. Gynekologicko-porodnicka klinika 1. To differentiate the effect of surgery on different types of pelvic pain.

METHODS: Patients with 1st to 3rd stage endometriosis, with manifestation of pelvic pain, and with complete excision of peritoneal endometriosis lesions, were included in the study. All visible lesions were vaporized by CO2 laser following adhesiolysis and complete visualization of the pelvis.

After the procedure, patients were followed up at 6-month intervals. The severity of pelipathia, dyspareunia, dysmenorrhea, pain during micturition, and pain during defecation were monitored using a visual analog score of 10 points. The proportion of recurrences increases with the length of the interval after the procedure, mainly in dysmenorrhea and dyspareunia. A graduated increase in the of recurrences is apparent during follow-up, most ificantly in dysmenorrhea and dyspareunia. The effect of surgery on different types of pelvic pain varies. A small of recurrences was found in pain during micturition and pain during defecation, on the other hand, less success was apparent in the treatment of dysmenorrhea.

To consider the role of different intensity of apoptosis in the progression of the disease and in the manifestation of clinical symptoms. Specimens were fixed in the Karnowski solution. The presence of apoptosis was assessed immunohistochemically.

Altogether, 29 patients were symptomatic, and 19 did not complain of any symptoms.

The average duration of symptoms was The presence of apoptosis was detected in 11 out of 35 evaluated specimens. In comparing the groups with and without apoptosis, no differences were found in the stage of the disease, in the proportion of asymptomatic patients, and in the manifestation of different subjective complaints. However, there were no relationships found between the presence of apoptosis and the stage of the disease or manifestation or character of subjective complaints.

Related Articles, Links Characteristics predictive of response to ovarian diathermy in women with polycystic ovarian syndrome. Factors predictive of pregnancy in our study group included younger age, lower body weight, and surgery before Related Articles, Links Tips on treating teens with endometriosis.

Ballweg ML. Sexe Denver Colorado ben rejeb MRI lesions correlated with those identified by laparoscopy 50 of or pathology 38 of Related Articles, Links Familial Mediterranean fever presenting as recurrent acute pelvic inflammatory disease. The differential diagnosis should include reinfection, appendicitis, endometriosis, irritable bowel syndrome, colitis, persistent ovarian cyst, and antibiotic-resistant bacterial strains. CASE: NA young Palestinian woman presented with recurrent episodes of pelvic pain with rebound tenderness, fever, and elevated white blood cell count, erythrocyte sedimentation rate, and C-reactive protein.

The patient underwent extensive workup, multiple courses of intravenous and oral antibiotics, and diagnostic laparoscopies, with continued recurrent episodes. Treatment with colchicine for suspected familial Mediterranean fever resulted in resolution of symptoms. Related Articles, Links Increased vascular surface density in ovarian endometriosis. Our goal in this study was to investigate the presence of angiogenesis-related factors in endometriomas by evaluating their vascular surface densities. Thirty ovarian samples were included in the study.

Of these, ten were histologically confirmed endometriomas, ten were ovarian specimens in the follicular phase and ten were ovarian specimens in the luteal phase, serving as controls. The area with the highest microvessel density in endometriosis and in the normal ovary was evaluated by using an intercept grid.

All microvessels in a specific field x magnification were counted and vascular surface density was measured, as The mean vascular surface density was ificantly higher in endometriosis than in the ovarian samples of the follicular phase or the luteal phase. No ificant difference was seen between normal ovarian samples. Endometriosis was associated with angiogenic properties. Having demonstrated elevated angiogenic factors in endometriotic samples, we concluded that activation of angiogenesis might be a key factor in the pathogenesis of endometriosis.

The histologic dating of endometrium was performed during cycle days and serum TSH, FSH, LH, prolactin, and estradiol levels were measured during the early follicular phase cycle day 3. Progesterone serum levels were measured in three different occasions during the luteal phase. Related Articles, Links Influence of missense mutation and silent mutation of LHbeta-subunit gene in Japanese patients with ovulatory disorders.

Associated data

The frequency of variant LHbeta containing two point mutations T -C and T -C and its relationship to reproductive disorders differ widely between ethnic groups. In a Japanese population, variant luteinizing hormone LH correlates with ovulatory disorders.

We studied 43 patients with ovulatory disorders, 79 patients with normal ovulatory cycles, and 23 healthy men who agreed to our DNA analysis. PCR-amplified LHbeta-subunit gene sequences were compared with a base sequence of wild-type LH reported after direct sequencing.

The influence of the rs genotypes of leptin receptor gene on the demographic and metabolic profile of normal saudi females and those suffering from polycystic ovarian syndrome

The highest frequency 0. No homozygotes for wild-type LHbeta C were identified.

The frequency of novel allele in patients with polycystic ovary syndrome, endometriosis, premature ovarian failure and luteal insufficiency was ificantly different from that of healthy women. The frequencies of novel alleles C -T, C -T and C -T in patients with ovulatory disorders were ificantly higher than those with normal ovulatory cycles.

The mean incidence of point mutation in patients with ovulatory disorders was higher than in those with normal ovulatory cycles. Among patients with variant LH, five silent mutations were identified in European Journal of Human Genetics 11, Related Articles, Links Spontaneous ovarian tumors in twelve baboons: a review of ovarian neoplasms in non-human primates. These included four granulosa cell tumors, three teratomas, two endometrioid carcinomas, one seromucinous cystadenofibroma, a cystic papillary adenocarcinoma, and an ovarian carcinoma.

Age was a pre-disposing factor. With one exception, the tumors of surface epithelial- and sex cordstromal origin occurred in baboons over 17 years of age. The exceptional animal was 7 years of age when a malignant granulosa cell tumor with Sertoli cell differentiation was identified. The two endometrioid tumors, which were found in and year-old animals, were both associated with endometriosis.

In contrast, the teratomas, which are tumors of germ cell origin, were found in younger animals, i.

One case of an ovarian carcinoma with metastases was observed in a 6-month-old infant. Cases of spontaneous ovarian tumors from the literature are reviewed. Related Articles, Links Record review of baboons with histologically confirmed endometriosis in a large established colony.

Thirty-seven have died; five remain alive; one was sold and lost to follow-up. The average age at diagnosis was When diagnosed by a palpable abdominal mass, there was a ificantly greater likelihood the animal died or was killed as a result of complications of endometriosis. When diagnosis was at necropsy, there was a ificantly greater likelihood that the animal died from causes unrelated to endometriosis.

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